Appropriate medical treatment must be available & provide close supervision if rare anaphylactic reaction occur following vaccination. Do not administer intravascularly. Individuals w/ thrombocytopenia or bleeding disorders. May induce a reduced immune response during immunosuppressive treatment or immunodeficiency condition; wait until the end of treatment before vaccinating. Syncope may occur; place procedures to prevent injury due to fainting & manage syncopal reactions. Contains phenylalanine, ethanol & Na. May be prescribed during pregnancy in high risk situations. Consider potential risk of apnoea & need for resp monitoring for 48-72 hr when administering primary immunisation series to very premature infants (≤28 wk of gestation) & particularly for those w/ previous history of resp immaturity.